Synapses are the connections between neurons. Without synapses, neurons are pretty much good for nothing. This study demonstrates how a molecule (NCAM2) essential to synaptic connections is broken down by the molecule called beta-amyloid, which is the main component of the plaques that build up in the brains of people with Alzheimer’s.
Links to the study together with articles about it have been posted in
Synapse Discovery Could Lead to New Treatments for Alzheimer’s Disease
Study: Synapse discovery could lead to new treatments for Alzheimer’s disease
Original article:
Aβ-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer’s disease
