A large new investigation, using over 94,000 people in the US and Europe with clinically diagnosed Alzheimer’s Disease, explored their genetic makeup with reference to that disease. The study revealed five new genetic variants that increase risk for Alzheimer’s. The work will will not immediately affect medical practice in the immediate future, but potentially will provide insights into brain/body interactions involved with dementia, and may help lead to treatments for young people who carry these genes.
Here are two media articles about the work:
Newly discovered Alzheimer’s genes further hope for future treatments
Alzheimer’s Disease Meta-Analysis Identifies Five New Risk Genes
Here is the NIH (National Institutes of Health) press release about the work:
Data sharing uncovers five new risk genes for Alzheimer’s disease
And here is the research publication:
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing